Efficacy of Bevacizumab Against Interface Neovascularization After Deep Anterior Lamellar Keratoplasty

Abstract

PURPOSE: We report a case of neovascularization at the interface after a deep anterior lamellar keratoplasty and its regression after a single bevacizumab injection. METHODS: Case report. RESULTS: We present a case of neovascularization and bleeding at the interface 2 days after a deep anterior lamellar keratoplasty for herpetic disease that was completely reversed by a single injection of bevacizumab at the interface. CONCLUSIONS: Corneal neovascularization is a typical sign of herpetic disease and one of the most important risk factors that can contribute to corneal graft failure. Close follow-up of patients at risk is necessary to detect and treat this complication as soon as possible to achieve a good outcome. Bevacizumab seems to be a successful and safe therapeutic option.