Induction of Abortion with Mifepristone (RU 486) and Oral or Vaginal Misoprostol

Abstract

Background. Medical termination of pregnancy can be successfully performed with a combination of mifepristone (RU 486) and a prostaglandin analogue. We conducted a prospective, randomized trial to compare oral with vaginal administration of the prostaglandin E 1 analogue misoprostol for first-trimester abortion in women treated initially with mifepristone.