A LARGE-SCALE EPIDEMIC OF HAND, FOOT AND MOUTH DISEASE ASSOCIATED WITH ENTEROVIRUS 71 INFECTION IN JAPAN IN 1978

Abstract

An epidemic of hand, foot and mouth disease (HFMD) took place throughout Japan in 1978. A total of 36,301 cases were reported and clinical symptoms were mostly typical of HFMD. Most patients were under five years of age. This communication deals with the summarized results of epidemiological informa tion from various laboratories on the incidence of HFMD.