Archives of Environmental Health An International Journal · 1974 · 61 citations · 8 references
PharmacyNutritionToxicologyExperimental PathologyOccupational ToxicologyRadiobiologyCarcinogenicity Of Dietary ExposuresMineral PhysiologyOccupational CarcinogenesisAsbestos-induced Lung DiseaseAsbestos-related DiseaseAsbestos-related Lung DiseaseAsbestosisFiber ToxicologyFibersTissue PenetrationTissue Penetration Efficiency
Abstract Three different laboratories independently investigated the ability of ingested mineral fibers to penetrate tissues in rats. All concluded that there was no evidence of tissue penetration by ingested mineral fibers. These experimental observations are supported by the findings in coal and hard-rock miners who swallow, during their lifetime, nearly 100 times the amount of dust that is stored in their lungs. The intestinal wall or mesenteric lymph nodes of these people show no evidence of storage of the ingested dust particles. Animals fed asbestos over much of their lifetime and allowed to live to the age of cancer production, failed to provide evidence of a cancerogenic effect.
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Lymphatics, Lymph and Tissue Fluid.
Penetration of Asbestos through the Digestive Tract of Rats
R. D. Pontefract, H. Μ. Cunningham · Nature · 1973 · 68 citations
Paul Gross, Robert T. P. deTrevïlle, Ethel B. Tolker et al. · Archives of Environmental Health An International Journal · 1967 · 66 citations
Lymphatics, Lymph and Tissue Fluid
American Journal of Clinical Pathology · 1933 · 63 citations · Full text
PHAGOCYTOSIS OF FOREIGN MATERIAL IN THE LUNG
O. H. Robertson · Physiological Reviews · 1941 · 49 citations
Medicine, Immunology, Pathology +10