The Consultant Pharmacist · 2010 · 48 citations · 10 references
PharmacyGeriatric MedicinePharmacy PracticeGeriatric CareGeriatric PharmacotherapyGeriatricsMedication Appropriateness ReviewMedication ReviewMedication UsePharmacoepidemiologyPolypharmacy ManagementPotentially Inappropriate MedicationsAge-based PrescribingGeriatric Medication AssessmentGeriatric Prescribing CriteriaHealth Care Cost SavingsInappropriate Medication Use ScreeningMedication ListsPotentially Inappropriate Prescribing Criteria
OBJECTIVE: Pharmacists' interventions of potentially inappropriate medications (PIM) decrease hospital admissions and emergency department visits and provide health-cost savings. The newest criterion to address PIMs is STOPP/START (Screening Tool of Older Person's Prescriptions/Screening Tool to Alert Doctor's to the Right Treatment). The purpose of this study is to determine the frequency of PIMs in a geriatric population. DESIGN/SETTING/PARTICIPANTS: A retrospective chart review of 511 patients was conducted at a Veterans Affairs hospital in patients > 70 years of age. INTERVENTIONS: Charts were reviewed at hospital admission, discharge, and first follow-up clinic visit post-discharge for incidence of STOPP/START medications. MAIN OUTCOME MEASURE(S): STOPP/START criterion was applied to patients' medication lists and documented with omission or commission medications. RESULTS: One hundred eleven (22%) patients met inclusion criteria. STOPP/START medication use was similar at all time points. Medications without an appropriate diagnosis were the most common type of STOPP criteria identified. Aspirin (> 150 mg daily) had high frequency of use. Incidence of START was highest with omissions of statin therapy, angiotensin-converting enzyme (ACE) inhibitor with heart failure, and vitamin D in patients with osteoporosis. CONCLUSION: The results demonstrated that inappropriate prescribing and omission of medications occurs consistently at all points of care. STOPP/START criteria are more comprehensive than previous inappropriate prescribing lists. Utilization of a clinical pharmacist would benefit patients through elimination of PIMs and identification of medications to optimize patient care.
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Paul Gallagher, Cristín Ryan, Shauna E. Byrne et al. · International Journal of Clinical Pharmacology and Therapeutics · 2008 · 1.5K citations