Physiological Effect of Tocotrienol

Abstract

Antitumor effect of tocotrienol was tested on murine tumor. IMC carcinoma cells were inoculated intraperitoneally (ip) into CDF1 mouse (6 week old, female), and mice were given ip injections of tocotrienol. Ten successive injections of α-tocotrienol (> 90%) gave a increase in life span of 248% at a dose of 100 mg/kg/day, and number of 60-day survivors was 4 out of 5 mice.