Concepedia

In vitro transendothelial migration of blood T lymphocytes from HIV-infected individuals

Jussi Saukkonen, Susanna Furfaro, Kathleen M. Mahoney, Robert M. Strieter, Marie D. Burdick, Erica A. Wright, Harvey Kornfeld, Jeffrey S. Berman

AIDS · 1997 · 12 citations · 37 references

DOI

Abstract

These data suggest that, in HIV-positive individuals, CD4+ T cells are migration competent and blood CD8+ T cells do not have enhanced migration competence relative to CD4+ T cells. CD8+ T cell extravasation is aided by TNF-alpha and IFN-gamma-induced endothelial cells activation.

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