BCRP gene expression is associated with a poor response to remission induction therapy in childhood acute myeloid leukemia

A multidrug resistance transporter from human MCF-7 breast cancer cells

L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences · 1998 · 2.3K citations

Medicine, Oncology, Pharmacology +16

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

Marc Maliepaard, George L. Scheffer, Ian F. Faneyte et al. · PubMed · 2001 · 1.1K citations

Medicine, Cancer Biology, Oncology +14

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

Keisuke Miyake, Lyn A. Mickley, Thomas Litman et al. · PubMed · 1999 · 822 citations · Full text

Medicine, Molecular Biology, Oncology +14

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance.

R Allikmets, Lynn M. Schriml, Amy Hutchinson et al. · PubMed · 1998 · 800 citations

Life Sciences, Genetics, Molecular Genetics +14

Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study.

Catherine P. Leith, Kenneth J. Kopecky, I‐Ming Chen et al. · PubMed · 1999 · 579 citations · Full text

Medicine, Oncology, Pharmacology +13