Synthesis and evaluation of donepezil–ferulic acid hybrids as multi-target-directed ligands against Alzheimer's disease

Wei Xu, Xiaobing Wang, Zhimin Wang, Jia‐Jia Wu, Fan Li, Jin Wang, Ling-Yi Kong

MedChemComm · 2016 · 57 citations · 33 references

Concepts

Abstract

A novel family of donepezil–ferulic acid hybrids were designed, synthesized and biologically evaluated as multi-target-directed ligands against Alzheimer's disease by fusing a fragment of donepezil and ferulic acid.

References

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