Effects of Corneal Cross-Linking on Ocular Response Analyzer Waveform-Derived Variables in Keratoconus and Postrefractive Surgery Ectasia

Abstract

Changes in a small subset of investigator-derived variables suggested an increase in corneal bending resistance after CXL. However, the magnitudes of these changes were low and not commensurate with the degree of clinical improvement or prior computational estimates of corneal stiffening in the same cohort over the same period. Available air-puff-derived measures of the corneal deformation response underestimate the biomechanical changes produced by CXL.