Pathogenesis of Arterial Hypertension in Coarctation of the Aorta

Abstract

ConclusionsPartial (or even complete) occlusion of the aorta rats produces hypertension only if there is living renal tissue distal to the occlusion, just as there must be a kidney beyond a partially occluded renal artery in order to produce hypertension in a Goldblatt dog. The same degree of mechanical obstruction due to stenosis of the aorta and the presence of a collateral bed never results in hypertension when all of the renal tissue is above the site of occlusion.