American Journal of Science · 1977 · 349 citations · 0 references
MedicineInternal MedicineNeurologyAlcohol ToxicologyHepatologyHepatotoxicologyChronic Liver DiseaseHepatic EncephalopathyHepatic ImpairmentHepatic PathophysiologyHepatic Vascular DisordersLiver DiseaseAlcohol-related Liver InjuryAlcoholic Liver Disease ProgressionDevolatilizationDevolatilization ReactionsLaboratory EvidenceLaboratory TestingLiver Disease ComplicationsPortosystemic Shunts
In an elderly male patient with alcohol-related liver disease, who developed episodic confusion and tremor, we found a large extrahepatic portacaval shunt. He had no clinical or laboratory evidence of liver dysfunction except for an elevated serum ammonia level that increased further in response to an ammonium chloride challenge test. Extrahepatic portacaval shunting causing episodic confusion and tremor may occur with alcoholic liver disease without overt liver failure and may require abdominal angiography or a transhepatic portogram to demonstrate the shunt.