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SEGREGATION OF LAMBDA LYSOGENICITY DURING BACTERIAL RECOMBINATION IN E. COLI K-12
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1953
Year
GeneticsBacteriologyBacteriophageMolecular BiologyMolecular GeneticsBacterial PathogensGalactose MarkerSimple Compatibility GeneVirulence FactorMolecular MicrobiologyBiologyNatural SciencesPathogenesisGenetic EngineeringLambda LysogenicityMicrobiologyRecombination DynamicMedicineMicrobial Genetics
Lederberg and Lederberg (1953) and Wollman (1953) have shown that in lysogenic by non-lysogenic crosses of E. coli K-12, lambda lysogenicity is closely linked to a galactose marker, although Wollman has suggested the possibility that neither character plays any part in genetic recombination. A genetic component of lysogenicity must therefore exist in the system lambda-E. coli K-12. Whether it is a simple compatibility gene, or controls the stability of cytoplasmic particles or whether more than a single bacterial gene is involved we cannot tell from lysogenic by non-lysogenic crosses alone.