Concepedia

IN VITRO-IN VIVO STUDIES OF BENZOTHIAZINES AGAINST LYMPHOCYTIC LEUKEMIA P388 CELLS

D. Todorov, M. Ilarionova, R. Gupta, J. Molnár, Noboru Motohashi

Heterocyclic Communications · 1995 · 10 citations · 4 references

DOIFull text

Open access

Concepts

Abstract

Seven benzothiazines have been screened for in vitro-in vivo cytotoxicity for the surviving cell fraction of lymphocytic leukemia P388 cells. Benzothiazines tested exhibit a slight direct cytotoxic activity.

References

4

Jpn. Kokai Tokkyo Koho JP 05, 112, 559

H. Shimamure · Medical Entomology and Zoology · 1993 · 481 citations

, , +2

Synthetic and spectral investigation of fluorinated phenothiazines and 4H-1,4-benzothiazines as potent anticancer agents

R. Gupta, M. Jain, R.S. Rathore et al. · Journal of Fluorine Chemistry · 1993 · 32 citations

, , +12

Anticancer activities of 2,3-dihydro-1,4-benzothiazines, and of their 4-(N-alkyl amides) and 4-(N-alkyl N-nitrosoamides)

R. Gupta, P.K. Dev, M L Sharma et al. · Anti-Cancer Drugs · 1993 · 31 citations

, , +10

Antimicrobial activity of phenothiazines, benzo[a]phenothiazines and benz[c]acridines.

Noboru Motohashi, Hiroshi Sakagami, T. KURIHARA et al. · PubMed · 1992 · 29 citations

, , +7