¹⁵N Hyperpolarization by Reversible Exchange Using SABRE-SHEATH

Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR

Jan Henrik Ardenkjær‐Larsen, Björn Fridlund, Andreas Gram et al. · Proceedings of the National Academy of Sciences · 2003 · 2.8K citations · Full text

Natural Sciences, Biophysics, Chemistry +17

Metabolic Imaging of Patients with Prostate Cancer Using Hyperpolarized [1- ¹³ C]Pyruvate

Sarah J. Nelson, John Kurhanewicz, Daniel B. Vigneron et al. · Science Translational Medicine · 2013 · 1.3K citations · Full text

Medicine, Oncology, Radiology +16

Parahydrogen and synthesis allow dramatically enhanced nuclear alignment

Clifford R. Bowers, D. P. Weitekamp · Journal of the American Chemical Society · 1987 · 1K citations

Natural Sciences, Chemistry, Nuclear Chemistry +5

Reversible Interactions with para-Hydrogen Enhance NMR Sensitivity by Polarization Transfer

Ralph W. Adams, Juan A. Aguilar, Kevin D. Atkinson et al. · Science · 2009 · 1K citations · Full text

Natural Sciences, Chemistry, Physics +16

Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy

Sam E. Day, Mikko I. Kettunen, Ferdia A. Gallagher et al. · Nature Medicine · 2007 · 884 citations

Medicine, Oncology, Radiology +14