The telomerase reverse transcriptase promoter drives efficacious tumor suicide gene therapy while preventing hepatotoxicity encountered with constitutive promoters

The serial cultivation of human diploid cell strains

Leonard Hayflick, Paul S. Moorhead · Experimental Cell Research · 1961 · 8.3K citations

Human Cell, Cell Division, Genetics +5

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

Telomerase Activity, Pathology, Human Telomerase Activity +17

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.6K citations

Fibrosis, Aging, Longevity +4

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

Toru Nakamura, Gregg B. Morin, Karen Chapman et al. · Science · 1997 · 2.3K citations · Full text

Catalytic Protein Subunits, Chromatin, Telomerase Catalytic Subunits +13

The RNA Component of Human Telomerase

Junli Feng, Walter D. Funk, Sy-Shi Wang et al. · Science · 1995 · 2.2K citations