Efficacy and safety of multiple doses of QGE031 (ligelizumab) versus omalizumab and placebo in inhibiting allergen-induced early asthmatic responses

Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma

William W. Busse, Jonathan Corren, Bobby Q. Lanier et al. · Journal of Allergy and Clinical Immunology · 2001 · 1.3K citations · Full text

Life Sciences, Immunology, Pharmacology +16

Down-regulation of Fc(ε)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody

Donald W. MacGlashan, Bruce S. Bochner, D C Adelman et al. · The Journal of Immunology · 1997 · 822 citations · Full text

Life Sciences, Immunology, Allergy +14

The Effect of an Anti-IgE Monoclonal Antibody on the Early- and Late-Phase Responses to Allergen Inhalation in Asthmatic Subjects

John V. Fahy, Hannah Fleming, Hofer Wong et al. · American Journal of Respiratory and Critical Care Medicine · 1997 · 715 citations

Life Sciences, Immunology, Pharmacotherapy +16

Effects of Treatment with Anti-immunoglobulin E Antibody Omalizumab on Airway Inflammation in Allergic Asthma

Ratko Djukanović, Susan J. Wilson, Monica Kraft et al. · American Journal of Respiratory and Critical Care Medicine · 2004 · 648 citations

Life Sciences, Immunology, Pharmacotherapy +16

Omalizumab-induced reductions in mast cell FcεRI expression and function

Lisa A. Beck, Gregory V. Marcotte, Donald MacGlashan et al. · Journal of Allergy and Clinical Immunology · 2004 · 447 citations

Life Sciences, Cell Biology, Immunology +14