Organic Letters · 2014 · 26 citations · 13 references
Life SciencesBotanyPlant SciencesPlant BiochemistryPlant PhysiologyStructure-activity RelationshipsAntioxidant DefenseFood AntioxidantsMedicinal PlantsReactive Oxygen SpeciesStructure-activity Relationship AnalysisAntioxidant Defense MechanismsAntioxidant Natural ProductsBioactive Plant CompoundsCaco-2 Cell AssayPlant Antioxidant DefensePlant Extract AntioxidantsX-ray Diffraction Analysis
Six unique nortriterpenoids, lancifonins A-F (1-6), were isolated from Schisandra lancifolia. Their absolute configurations were determined by X-ray diffraction and ECD calculation. The conformational analysis of 1 was performed due to the unanticipated changes of Cotton effects in its ECD spectrum. Compounds 5 and 6 possess a unique 7/7 fused carbocyclic core with an internal ester bridge between C-9 and C-14, and 5 exhibited protective activity against H2O2-induced oxidative damage on Caco-2 cells.
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Diastereoselective Total Synthesis of (±)‐Schindilactone A
Qing Xiao, Weiwu Ren, Zhixing Chen et al. · Angewandte Chemie International Edition · 2011 · 164 citations
Metal-Catalyzed Syntheses of Abridged CDE Rings of Rubriflordilactones A and B
Shermin S. Goh, Hannah Baars, B. Gockel et al. · Organic Letters · 2012 · 58 citations