Fenton-like Reaction-Mediated Etching of Gold Nanorods for Visual Detection of Co²⁺

Abstract

We have proposed a Fenton-like reaction-mediated etching of gold nanorods and applied it to the sensitive visual detection of Co(2+) ions. With the presence of bicarbonate (HCO3(-)) and hydrogen peroxide(H2O2), Co(2+) ions trigger a Fenton-like reaction, resulting in the generation of superoxide radical (O2(•-)). As a result, the gold nanorods are gradually etched by O2(•-) in the presence of SCN(-), accompanied by an obvious color change from green to red. The gold nanorods etching process preferentially occurs along the longitudinal direction, which is observed by transmission electron microscope. The etching mechanism is carefully proved by investigating the effects of different radical scavengers (e.g., dimethyl sulfoxide). The auto-oxidation of hydroxylamine assay further confirms the mechanism. Then, the main factors, including reactants concentrations, temperature, and incubation time, are specifically investigated. Under optimized conditions, we get an excellent sensing performance for Co(2+) with a lower detection limit of 1.0 nM via a spectrophotometer and a visual detection limit of 40 nM. In addition, this principle may provide a new concept of "intermediate-mediated etching of nanoparticles" for sensing.