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Central Inhibitory Effects of Carbon Dioxide. III. Man
31
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0
References
1949
Year
Carbon DioxidePharmacotherapySummaryeighteen PatientsExperimental PharmacologySocial SciencesInhibitory ActivityRespiratory NeurobiologyCarbon SequestrationCarbon Dioxide-oxygenAnesthesia PracticeNeuropharmacologyOxygen TherapyRespiration (Physiology)PharmacologyCardiac ArrestNeurophysiologyPhysiologyElectrophysiologyAnesthesiaMedicineAnesthesiology
SummaryEighteen patients were ventilated with various concentrations of carbon dioxide-oxygen for varying lengths of time and then were stimulated with super-threshold shocking current. Concentrations of carbon dioxide from 15-30% routinely prevented electrically induced seizures; with 30% carbon dioxide, 30 seconds of inhalation sufficed; with 15-20% mixtures, slightly longer periods of time were required.