Erbium(III) Chloride in Ethyl Lactate as a Smart Ecofriendly System for Efficient and Rapid Stereoselective Synthesis of <i>trans</i>-4,5-Diaminocyclopent-2-enones

Abstract

Erbium(III) chloride in ethyl lactate is used as an environmentally very friendly system for the reaction of furfural and amines to yield diastereoselectively differently N,N-substituted trans-4,5-diaminocyclopent-2-enones as versatile synthetic intermediates to the formation of densely functionalized derivatives.