Potential Use of Contrast-Enhanced Ultrasound (CEUS) in the Detection of Metastatic Superficial Lymph Nodes in Melanoma Patients

Abstract

CEUS increases the diagnostic accuracy of US in the differential diagnosis of benign and malignant LNs but it also allows us, when possible, to avoid unnecessary invasive operations such as LN FNAC. Moreover, CEUS may guide FNAC in the case of focal cortical thickening on the basis of hypoperfusion, with a reduction in the number of false negatives and much earlier detection of nodal metastatic foci.