Effect of Positive End-Expiratory Pressure on Central Venous Pressure in Patients under Mechanical Ventilation.

Abstract

The findings of this study revealed the direct relationship between PEEP and CVP. Approximately, a 5 cmH₂O increase in PEEP will be associated with about 2.5 cmH₂O raise in CVP. When applying a 5 cmH₂O PEEP increase, if the baseline PEEP is 0, it leads to a significantly higher raise in CVP compared to when it is 5 cmH₂O (2.5 vs. 1.6). It seems that sex, history of cardiac failure, baseline CVP level, and hypertension do not have a significant effect in this regard.