Studies on bioactive substances in crude drugs used for arthritic diseases in traditional Chinese medicine. II. Isolation and identification of an anti-inflammatory and analgesic principle from the root of Angelica pubescens MAXIM.

Abstract

The methanol extract of the root of Angelica pubescens MAXIM. was fractionated, and, by following the inhibitory activities on rat hind paw edema induced by carrageenan and on writhing induced by acetic acid in mouse, the active principle was isolated and identified as osthol.