Synthesis of Biologically Active Triazenes from Isolable Diazonium Salts

Abstract

Alkaryl triazenes were synthesized in two steps from the isolated intermediary diazonium tetrafluoroborates and hexafluorophosphates by coupling the arenediazonium cations with dimethylamine in an aqueous solution but without the use of mineral base. The method enables the preparation of triazenes which are not readily accessible by conventional procedures; it also leads to higher yields and purer products in the preparation of known compounds.