Effect of Aspirin Administration on Serum Glutamic Oxaloacetic and Glutamic Pyruvic Transaminases in Children.

Abstract

The effect of aspirin and of sodium salicylate administration on the serum glutamic oxaloacetic transaminase activity in 14 children and its effect on both the serum glutamic oxaloacetic transaminase and the serum glutamic pyruvic transaminase in an additional 9 children has been studied. Elevations to abnormal levels were observed in more than 50% of the cases. The importance of this finding in relation to the interpretation of the serum glutamic oxaloacetic transaminase elevations in rheumatic fever is pointed out and some possible underlying reasons for this phenomenon are mentioned.