The Pediatric Infectious Disease Journal · 2011 · 29 citations · 1 references
MedicineImmunologyInternal MedicineClinical ImmunologyImmunopathologyInflammationDiagnostic Test EvaluationInflammatory BiomarkersBiomarkers Of Disease PrognosisHigh-sensitivity AssaysLogistic RegressionLogistic Regression AnalysisPrognostic Inflammatory BiomarkersPrognostic Marker Assessment
We measured serum procalcitonin concentrations in 160 patients suffering from Kawasaki disease. Serum procalcitonin was significantly higher in nonresponders to an initial intravenous immunoglobulin treatment than in responders. A cutoff value of procalcitonin (0.5 ng/mL) for nonresponders showed that the sensitivity was 85% and the accuracy was 64%. Multivariate logistic regression analysis revealed that procalcitonin-positive cases showed the highest risk for nonresponders.
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