Thyroiditis Resulting from Administration of Excess Iodine to Hamsters with Hyperplastic Goiters.

Abstract

SummaryAdministration of large amounts of iodine to hamsters which have hyperplastic goiters produced by an iodine-deficient diet or by a goitrogen results in a morphologic response which is different from that encountered when iodine is given in physiological amounts. An acute inflammatory reaction and a diminution of the accumulation of colloid are found, neither of which has been observed in animals treated with smaller amounts of iodine.