Concepedia

Publication | Closed Access

Magnetic Nanoparticles and Rapamycin Encapsulated into Polymeric Nanocarriers

DOI

31

Citations

0

References

2012

Year

Relton Romeis Oliveira, Fabrícia Saba Ferreira, Emílio R. Cintra, Luis César Branquinho, Andris F. Bakuzis, Eliana Martins Lima
Journal of Biomedical Nanotechnology

Abstract

Non-contact AFM images showed that the composite nanoparticles were almost spherical in shape. The resulting polymeric nanocarriers were found to have a mean diameter of approximately 120 nm with a narrow size distribution. The influence of some experimental parameters on the entrapment efficiency and stability was determined. Nanocapsules and nanospheres prepared with uncoated magnetic nanoparticles exhibited higher entrapment efficiency and stability. Superparamagnetic behavior of the magnetic nanocomposite was demonstrated by magnetization data. These findings may contribute to the development of potential controlled release drug targeting devices based on magnetic polymeric nanocarriers.