Gadolinium Containing Contrast Agents for Pulmonary Ventilation Magnetic Resonance Imaging

Abstract

The use of gadolinium for MR ventilation imaging is primarily hindered by its viscosity properties and thus, its capability of aerosolization. Of the five agents tested, the medium with the lowest viscosity at room temperature (gadoteridol) showed the most promising enhancement results. The results reaffirm the potential of gadolinium-based contrast agents as a pulmonary imaging alternative. With a reduction of ventilation duration down to ten minutes, the method appears tolerable in a clinical setting.