New England Journal of Medicine · 1964 · 35 citations · 2 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceDiagnostic MicrobiologyMedical MicrobiologyAntibacterial PharmacotherapyAntibacterial ResistanceAntibacterial TherapyAntibiotic ResistanceBacterial InfectionsPulmonary InfectionsBacterial Pneumonia TreatmentOral Tetracycline TherapyPenicillin ResistancePneumococcal DiseasePneumococcal Pneumonia TreatmentPneumonia Antibiotic TherapyTetracycline AntibioticsTetracycline Resistance Mechanisms
ALTHOUGH penicillin is the drug of choice in the treatment of pneumococcal infections these infections usually respond well to early and adequate therapy with tetracycline.1 Tetracycline is now prescribed frequently for suspected pneumococcal pneumonia, especially in the cases in which rapid bacteriologie diagnosis is not available or in which the patient is unable to tolerate penicillin.We report here the isolation, from 2 patients, of pneumococci exhibiting high levels of resistance to tetracycline in vitro. One of these patients acquired classic pneumococcal pneumonia while on tetracycline therapy.Case ReportIn February, 1963, a tetracycline-resistant Type 14 pneumococcus was isolated . . .
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TETRACYCLINE-RESISTANT PNEUMOCOCCUS
W. Evans, David Hansman · The Lancet · 1963 · 58 citations
TETRACYCLINE-RESISTANT PNEUMOCOCCI
J.D.M. Richards, Julian Anthony Rycroft · The Lancet · 1963 · 19 citations