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Leukocyte Antigens and Disease: II. Association of HL-A5 and Lymphomas
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1972
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HistocompatibilityImmunohematologyLymphoid NeoplasiaViral ComponentWilliam A.Human Leukocyte AntigenMalignant Blood DisorderHla ImmunogeneticsImmunologyHematologyPathologyAutoimmunityLeukocyte AntigensHla TypingAdult T-cell Leukemia-lymphomaMedicineTissue CellsHealth Sciences
Rege, Vishram, Patel, Ramon, and Briggs, William A.: Leukocyte antigens and disease: II. Association of HL-A5 and lymphomas. Am. J. Clin. Pathol. 58: 14–16, 1972. A statistically significant association of the leukocyte antigens HL-A5 or W5 (which is included in HL-A5) and Hodgkin’s disease was confirmed. In addition, this study suggests that this association may extend to other types of lymphomas as well. Individuals with the leukocyte antigen HL-A5 (or W5) on their tissue cells may have an increased tendency to develop one or another type of lymphoma. Whether this is on the basis of a genetic or viral component, or both, remains unknown.