Enantioselective Manganese-Porphyrin-Catalyzed Epoxidation and C–H Hydroxylation with Hydrogen Peroxide in Water/Methanol Solutions

Abstract

The asymmetric epoxidation of alkene and hydroxylation of arylalkane derivatives by H(2)O(2) to give optically active epoxides (enantiomeric excess (ee) up to 68%) and alcohols (ee up to 57%), respectively, were carried out in water/methanol solutions using chiral water-soluble manganese porphyrins as catalysts.