New England Journal of Medicine · 2015 · 878 citations · 33 references
In this study, the selective BTK inhibitor acalabrutinib had promising safety and efficacy profiles in patients with relapsed CLL, including those with chromosome 17p13.1 deletion. (Funded by the Acerta Pharma and others; ClinicalTrials.gov number, NCT02029443.).
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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
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Targeting BTK with Ibrutinib in Relapsed or Refractory Mantle-Cell Lymphoma
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