Exogenous basic fibroblast growth factor promotes cardiac stem cell-mediated myocardial regeneration after miniswine acute myocardial infarction - Concepedia

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Exogenous basic fibroblast growth factor promotes cardiac stem cell-mediated myocardial regeneration after miniswine acute myocardial infarction

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2011

Year

Yuhai Zhang, Guangwei Zhang, Tianxiang Gu, Jesse Li‐Ling, Ti Wen, Ye Zhao, Chun Wang, Fang Qin, Lei Yu, Bo Liu

Coronary Artery Disease

Abstract

Exogenous bFGF was shown to have increased angiogenesis and myocardial perfusion, promoted myocardial regeneration by activating the SDF-1α/CXCR4 axis, and thereby improved the cardiac function, which may provide a new therapeutic strategy for AMI.