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The Mandatory Role of Lipid in the Interaction of Factors VIII and IX.
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1966
Year
InflammationFactor XFactors ViiiAllergyMedicinePhysiologyLipid DisordersHematologyImmunologyHemostasisFactor ViiiLipid ScienceActivated Factor ViiiPharmacologyMandatory RoleLipid DisorderHealth Sciences
1. An interaction between activated Factor IX and Factor VIII which is independent of Factor X has been confirmed using human reagents. The product, activated Factor VIII, is a very labile activity. 2. Lipid has been shown to be a mandatory cofactor in the interaction of Factor VIII and serum factors in the presence of thrombin.