Sulfoorientalols a, b, c, and d, four new biologically active sesquiterpenes, from alismatis rhizoma.

Abstract

Four new sesquiterpenes, sulfoorientalols a, b, c, and d, having a sulfonic acid function were isolated from Chinese Alismatis Rhizoma. Their structures were determined on the basis of chemical and physicochemical evidence. Sulfoorientalols inhibited the contraction of isolated bladder smooth muscle induced by carbachol.