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The toxic principles of Naematoloma fasciculare.
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1983
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Toxic PrinciplesMedicinal ChemistryPoisonous MushroomBiochemistryMedicineNatural SciencesFasciculol EPathologyNaematoloma FascicularePoisoningToxicologyExperimental ToxicologyPharmacologyClinical ToxicologyToxicological MechanismOxidative Stress
Fasciculol E and F were identified as the toxic principles of Naematoloma fasciculare (Nigakuritake), a poisonous mushroom. These compounds caused paralysis and death in mice. The LD50 values of fasciculol E and F to mice were determined as 50 mg/kg and 168 mg/kg (i. p.), respectively.