Chaetoglobosins, cytotoxic 10-(indol-3-yl)-(13)cytochalasans from Chaetomium spp. I. Production, isolation and some cytological effects of chaetoglobosins A-J.

Abstract

Bioproduction of chaetoglobosins, novel type cytochalasans, by Chaetomium spp. was examined. Details of the culture conditions and methods for separation of the metabolites of Chaetomium globosum are presented. Some cytological effects of chaetoglobosins were also mentioned.