LXII Scleroma: A Clinico-Pathological Study of Seven Cases in One Family

Abstract

1. A detailed study on seven cases of scleroma from one family is presented. 2. Histologic changes in the mucous membrane of the respiratory tract-from the incipient nasal catarrh, followed successively by suppurative rhinitis, atrophic rhinitis, chronic granuloma to the final deforming scleromatous scar-are shown. 3. Of the various therapeutic measures tried streptomycin 10 an adequate dose is the most promising. 4. A diagnosis of scleroma can be made by trained bacteriologists and serologists long before histologic changes are recognized. © 1947, SAGE Publications. All rights reserved.