Particle Size of Soluble Antigen of Rabies Virus

Abstract

1. A particle size of 12 m/μ has been determined by a method of diffusion coupled with biological assay for the soluble antigen of rabies extracted from infected suckling mouse brains. This value agrees with that calculated from the approximate sedimentation constant calculated from the sedimentation rate in the swinging bucket rotor of the Spinco ultracentrifuge. 2. No conclusions regarding the homogeneity of the soluble antigen can be drawn at this stage.