Microwave-Assisted Synthesis and Antitumor Activity of Salicyl Acyloxy Phosphonate Derivatives

Abstract

a a a a b ( a 563003) ( b 550025) , - DCC/DMAP , 12 , IR, 1 H NMR, 13 C NMR . : 15 mL CH 2 Cl 2 , 800 W, 3.5 h, , . (MTT) , : . 2f HEp-2 [IC 50 (13.90.6) mol/L][IC 50 (9.31.1) mol/L], 2k EC-109 [IC 50 (8.50.9) mol/L][IC 50 (5.91.0) mol/L]. ; -; ; ;