Experimental Biology and Medicine · 1950 · 29 citations · 0 references
FertilityPlacental ImplantsReproductive HealthGynecologyFemale Reproductive FunctionEmbryologyReproductive EndocrinologyReproductive PhysiologyImplantation (Embryology)Reproductive MedicinePublic HealthTest RatsPlacental Development12-Day PlacentaFirst PregnancyMaternal HealthPlacental DiseaseMaternal-fetal MedicineEndocrinologyPlacental FunctionPhysiologyPregnancyMedicine
Pregnancy has been maintained in rats hypophysectomized on day 6 of their first pregnancy and injected daily subcutaneously for 6 days with placentae from rats, 12 days pregnant. Five placentae or approximately 275 mg daily accomplished this in the majority of the test rats. One 12-day placenta plus 0.5 μg of estrone proved equally efficacious. Pregnancy was not maintained by similar treatment if the rats were also oöphorectomized.