Planar Mn₄O Cluster Homochiral Metal–Organic Framework for HPLC Separation of Pharmaceutically Important (±)-Ibuprofen Racemate

Abstract

A planar tetracoordinated oxygen containing a homochiral metal-organic framework (MOF) has been synthesized and characterized that can be used as a new chiral stationary phase in high-performance liquid chromatography to efficiently separate racemates such as pharmaceutically important (±)-ibuprofen and (±)-1-phenyl-1,2-ethanediol.