Publication | Open Access
Poly(ethylene) glycols and mechanochemistry for the preparation of bioactive 3,5-disubstituted hydantoins
73
Citations
39
References
2016
Year
Derivative (Chemistry)Pharmaceutical ChemistryBioorganic ChemistryEngineeringOrganic ChemistryAlkyl Isocyanates3,5-Disubstituted HydantoinsPharmacologyα-Amino Methyl EstersSynthetic ChemistryBio-orthogonal ChemistryBiomolecular EngineeringBioactive 3,5-Disubstituted Hydantoins
Mechanochemistry was effective for the preparation of 3,5-disubstituted hydantoins from α-amino methyl esters, using either 1,1′-carbonyldiimidazole (CDI) or alkyl isocyanates.
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