Urinary Excretion of Estrogens and 17-Ketosteroids in Young, Adult Males With Infectious Hepatitis

Abstract

The levels of excretion of estrogens and 17-ketosteroids in the urine have been determined in 11 young adult males with acute infectious hepatitis, at frequent intervals, from onset of the disease to convalescence. In 9 moderately severe cases there was a significant elevation in the level of excretion of biologically active estrogens in the urine which persisted at a slowly diminishing elevation until convalescence was considerably advanced. There was no significant increase in the concentration of the urinary estrogens in 2 cases of hepatitis which presented only mild clinical symptoms.