Eefcts of the hippocampal deep brain stimulation on cortical epileptic discharges in penicillin –induced epilepsy model in rats

Abstract

Our results revealed that continuous high frequency stimulation of the hippocampus suppressed acute cortical epileptic activity effectively without causing secondary epileptic discharges. These results are important in terms of defining the optimal parameters of hippocampal DBS in patients with epilepsy.