American Journal of Dermatopathology · 1990 · 37 citations · 0 references
MedicineDermatologyPathologyCellular PathologyHistopathologyImmunopathologyHelper T Cell SubsetsImmunopathology Of SkinLymph Node PathologyLymphoid TissueLymphoid Tissue PathologyT Cell BiologyAtypical CellsBullous DermatosesPeripheral Blood Lymphocyte AnalysisT Cell-mediated PathologyT Helper Cell BalanceT Helper CellsT-cell Mediated Skin Disease
A case of mycosis fungoides bullosa is presented. The results in our study confirmed that the predominant atypical lymphoid cells in the bullae, peripheral blood, and involved lymph nodes expressed the T-cell helper phenotype using immunophenotyping techniques. The literature is reviewed, confirming that our case demonstrated cells of the T-helper phenotype, not only in the skin but also in the blood and lymph node tissue. Bullous lesions in mycosis fungoides are rare.