Ionic liquid catalyzed one-pot synthesis of spiropyran derivatives via three-component reaction in water

Abstract

Abstract The ionic liquid [H 3 N + CH 2 CH 2 OH][CH 3 COO - ] (HEAA) catalyzes a three-component, one-pot condensation of malononitrile/ethyl cyanoacetate, 1,3-dicarbonyl compound/enol, and quinone or ninhydrin in water to afford a spiropyran derivative. This method has advantages of mild reaction conditions, short reaction time, and environmental friendliness.