A Novel Linear Code Nomenclature for Complex Carbohydrates.

Abstract

The Linear Code is a new syntax for representing glycoconjugates and their associated molecules in a simple linear fashion. Similar to the straightforward single letter nomenclature of DNA and proteins, Linear Code presents glycoconjugates in a canonic, compact and practical form while accounting for all relevant stereochemical and structural configurations. It uses a single letter code to represent each monosaccharide and includes a condensed description of the connections between monosaccharides and their modifications, allowing a simple linear representation of these compounds. The new linear syntax enables the implementation of bioinformatics tools for investigation and analysis of glyco-molecules and their biology.